Molecules/Elements/Particles

 

Monday
Oct312011

Phenol

"Phenol, also known as carbolic acid, phenic acid, is an organic compound with the chemical formula C6H5OH. It is a white crystalline solid. The molecule consists of a phenyl (-C6H5), bonded to a hydroxyl (-OH) group. It is produced on a large scale (about 7 billion kg/year) as a precursor to many materials and useful compounds.[4] It is only mildly acidic but requires careful handling due to its propensity to cause burns."

"Phenol was first extracted from coal tar, and its major uses involve its conversion to plastics or related materials. Phenols are key for building polycarbonates, epoxies, Bakelite, nylon, detergents and a large collection of drugs, herbicides and pharmaceuticals."

Sunday
Oct302011

Nylon

"Nylon is a thermoplastic, silky material, first used commercially in a nylon-bristled toothbrush (1938), followed more famously by women's stockings ("nylons"; 1940). It is made of repeating units linked by amide bonds and is frequently referred to as polyamide (PA). Nylon was the first commercially successful synthetic polymer. There are two common methods of making nylon for fiber applications. In one approach, molecules with an acid (-COOH) group on each end are reacted with molecules containing amine (-NH2) groups on each end. The resulting nylon is named on the basis of the number of carbon atoms separating the two acid groups and the two amines. These are formed into monomers of intermediate molecular weight, which are then reacted to form long polymer chains."

"Nylons are condensation copolymers formed by reacting equal parts of a diamine and a dicarboxylic acid, so that amides are formed at both ends of each monomer in a process analogous to polypeptide biopolymers. Chemical elements included are carbon, hydrogen, nitrogen, and oxygen. The numerical suffix specifies the numbers of carbons donated by the monomers; the diamine first and the diacid second. The most common variant is nylon 6-6 which refers to the fact that the diamine (hexamethylene diamine, IUPAC name: hexane-1,6-diamine) and the diacid (adipic acid, IUPAC name: hexanedioic acid) each donate 6 carbons to the polymer chain. As with other regular copolymers like polyesters and polyurethanes, the "repeating unit" consists of one of each monomer, so that they alternate in the chain. Since each monomer in this copolymer has the same reactive group on both ends, the direction of the amide bond reverses between each monomer, unlike natural polyamide proteins which have overall directionality: C terminal → N terminal. In the laboratory, nylon 6-6 can also be made using adipoyl chloride instead of adipic."

Saturday
Oct292011

Nickel Tetracarbonyl

Nickel carbonyl (IUPAC name: tetracarbonylnickel) is the organonickel compound with the chemical formula Ni(CO)4. This pale-yellow metal carbonyl is very volatile at room temperature and highly toxic. Nickel Carbonyl can be used to nickel coat steel and other metals and to make very pure nickel. It is an intermediate in the Mond process for the purification of nickel and is a reagent in organometallic chemistry.

Nickel carbonyl is a tetrahedral molecule with four carbonyl (carbon monoxide) ligands attached to nickel. The CO ligands, in which the C and the O are connected by triple bonds (often depicted as double bonds), are covalently bonded to the nickel atom via the carbon ends. The structures of nickel carbonyl and related compounds baffled chemists for many years,[why?] and most publications before 1950 depicted chains of CO chelated to the metal.

 

Friday
Oct282011

Insulin

"Insulin is a hormone central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle."

"Insulin stops the use of fat as an energy source by inhibiting the release of glucagon. With the exception of the metabolic disorder diabetes mellitus and Metabolic syndrome, insulin is provided within the body in a constant proportion to remove excess glucose from the blood, which otherwise would be toxic. When blood glucose levels fall below a certain level, the body begins to use stored sugar as an energy source through glycogenolysis, which breaks down the glycogen stored in the liver and muscles into glucose which can then be utilized as an energy source. As its level is a central metabolic control mechanism, its status is also used as a control signal to other body systems (such as amino acid uptake by body cells). In addition, it has several other anabolic effects throughout the body."

Wednesday
Oct262011

Mercaptans (Thiols)

"In organic chemistry, a thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (–C–SH or R–SH) group (where R represents an alkane, alkene, or other carbon-containing group of atoms). Thiols are the sulfur analogue of alcohols (that is, sulfur takes the place of oxygen in the hydroxyl group of an alcohol), and the word is a portmanteau of "thio" + "alcohol," with the first word deriving from Greek θεῖον ("thion") = "sulfur". The –SH functional group itself is referred to as either a thiol group or a sulfhydryl group."

"Many thiols have strong odors resembling that of garlic, and indeed the odor of garlic itself is due to a thiol. Thiols are used as odorants to assist in the detection of natural gas (which in pure form is odorless), and the "smell of natural gas" is due to the smell of the thiol used as the odorant."

"Thiols are often referred to as mercaptans. The term mercaptan is derived from the Latin mercurium captans (capturing mercury) because the thiolate group bonds so strongly with mercury compounds."

Tuesday
Oct252011

Trinitrotoluene (TNT)

"Trinitrotoluene (TNT), or more specifically, 2,4,6-trinitrotoluene, is a chemical compound with the formula C6H2(NO2)3CH3. This yellow-colored solid is sometimes used as a reagent in chemical synthesis, but it is best known as a useful explosive material with convenient handling properties. The explosive yield of TNT is considered to be the standard measure of strength of bombs and other explosives. In chemistry, TNT is used to generate charge transfer salts."

"TNT is one of the most commonly used explosives for military and industrial applications. It is valued partly because of its insensitivity to shock and friction, which reduces the risk of accidental detonation, compared to other more sensitive high explosives such as nitroglycerin. TNT melts at 80 °C (176 °F), far below the temperature at which it will spontaneously detonate, allowing it to be poured as well as safely combined with other explosives. TNT neither absorbs nor dissolves in water, which allows it to be used effectively in wet environments. Additionally, it is stable compared to other high explosives."

Monday
Oct242011

Adipic Acid

"Adipic acid is the organic compound with the formula (CH2)4(COOH)2. From the industrial perspective, it is the most important dicarboxylic acid: About 2.5 billion kilograms of this white crystalline powder are produced annually, mainly as a precursor for the production of nylon. Adipic acid otherwise rarely occurs in nature."

"Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of a hydrophilic drug. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Other controlled-release formulations have included adipic acid with the intention of obtaining a late-burst release profile."

Sunday
Oct232011

Benzophenone

"Benzophenone is the organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO. Benzophenone is a widely used building block in organic chemistry, being the parent diarylketone."

"Benzophenone can be used as a photo initiator in UV-curing applications such as inks, imaging, and clear coatings in the printing industry. Benzophenone prevents ultraviolet (UV) light from damaging scents and colors in products such as perfumes and soaps. It can also be added to the plastic packaging as a UV blocker. Its use allows manufacturers to package the product in clear glass or plastic. Without it, opaque or dark packaging would be required."

"In biological applications, benzophenones have been used extensively as photophysical probes to identify and map peptide–protein interactions."

Saturday
Oct222011

Triglycerides

"A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids.[1] There are many triglycerides, depending on the oil source, some are highly unsaturated, some less so. They are the main constituents of vegetable oil (typically more unsaturated) and animal fats (typically more saturated).[2] In humans, triglycerides are a mechanism for storing unused calories, and their high concentrations in blood correlates with the consumption of starchy and fatty foods.

Friday
Oct212011

Pyridine

"Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one C-H group replaced by a nitrogen atom. The pyridine ring occurs in many important compounds, including azines and the vitamins niacin and pyridoxal."

"Pyridine was discovered in 1849 by the Scottish chemist Thomas Anderson as one of the constituents of bone oil. Two years later, Anderson isolated pure pyridine through fractional distillation of the oil. It is a colorless, highly flammable, weakly alkaline, water-soluble liquid with a distinctive, unpleasant fish-like odor."

"Pyridine is used as a precursor to agrochemicals and pharmaceuticals and is also an important solvent and reagent. Pyridine is added to ethanol to make it unsuitable for drinking. It is used in the synthesis of sulfapyridine (a drug against bacterial and viral infections), antihistaminic drugs tripelennamine and mepyramine, as well as water repellents, bactericides and herbicides. Some chemical compounds, although not synthesized from pyridine, contain its ring structure. They include B vitamins niacin and pyridoxal, an anti-tuberculosis drug isoniazid, nicotine and other nitrogen-containing plant products.[5] Historically, pyridine was produced from coal tar and as a by-product of the coal gasification. However, increased demand for pyridine resulted in the development of more economical methods of synthesis from acetaldehyde and ammonia, and more than 20,000 tonnes per year are manufactured worldwide."